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European multiple system atrophy study group (LIFE QUALITY) (2001-03-01 - 2004-12-31)
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Werner POEWE,
Johannes JAKOBSEN,
Alain HERIAUD,
Jean-Pierre BASTARD,
William WAKEHAM,
Mireille BLANC,
Jürgen WEBER,
Sten WENNERSTROEM,
Horst Franz KERN,
Reinhard HOROSWSKI,
Gabriel BARBASH,
Ruth LEVY,
Jose Francisco DAVID FERREIRA,
Giampaolo CANTORE,
Hartmut WAGNER,
Joaquim AZCON,
Robert WALKER,
Ignacio IRIBARREN,
Primoz RODE,
Mats Ola OTTOSSON
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MEDIZINISCHE UNIVERSITAET INNSBRUCK (AT332 - Innsbruck) (Austria),
AARHUS UNIVERSITETS HOSPITAL - AARHUS UNIVERSITY HOSPITAL (DK00D - Århus amt) (Denmark),
CENTRE HOSPITALIER ET UNIVERSITAIRE DE BORDEAUX (FR612 - Gironde) (France),
CENTRE HOSPITALIER UNIVERSITAIRE DE GRENOBLE (FR714 - Isère) (France),
IMPERIAL COLLEGE LONDON (UK550 - Greater London) (Great Britain),
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR623 - Haute-Garonne) (France),
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE212 - München, Kreisfreie Stadt) (Germany),
LUNDS UNIVERSITET (SE043 - Malmoehus Laen) (Sweden),
PHILIPPS UNIVERSITAET MARBURG (DE724 - Marburg-Biedenkopf) (Germany),
SCHERING AG (DE300 - Berlin) (Germany),
TEL AVIV SOURASKY MEDICAL CENTER (ME04 - Israel) (Israel),
TEVA PHARMACEUTICAL INDUSTRIES LTD (ME04 - Israel) (Israel),
UNIVERSIDADE DE LISBOA (PT132 - Grande Lisboa) (Portugal),
UNIVERSITA DEGLI STUDI DI ROMA "LA SAPIENZA" (ITE43 - Roma) (Italy),
UNIVERSITAET BONN (DEA22 - Bonn, Kreisfreie Stadt) (Germany),
UNIVERSITAT DE BARCELONA (ES511 - Barcelona) (Spain),
UNIVERSITY COLLEGE LONDON (UK550 - Greater London) (Great Britain),
UNIVERSITY HOSPITAL "MARQUES DE VALDECILLA" (ES130 - Cantabria) (Spain),
UNIVERSITY MEDICAL CENTER LJUBLJANA (SI00E - Osrednjeslovenska) (Slovenia),
UPPSALA UNIVERSITET (SE021 - Uppsala län) (Sweden) |
| BUDGET: | 543.634 € |
| FUNDING: | 543.634 € |
| INSTRUMENT: | Coordination of Research Actions |
| PROGRAMME: | LIFE QUALITY |
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Multiple system atrophy (MSA) is a progressive neurodegenerative disorder, which frequently presents with the features of Parkinson's Disease, but in contrast to latter, causes early death and prolonged severe disability. The proposed concerted action will pave the way towards neuroprotective intervention trials in MSA by developing a trial protocol 'CAPIT-MSA) and by implementing a central MSA Registry (EMSA-R) for centralized data acquisition during a multicoated natural history study that will enable us to define rates of disease progression and to validate the CAPIT-MSA protocol. Furthermore, candidate neuroprotective agents will be screened in proof of concept studies using an established animal model of striatonigral degeneration. Pending ongoing preclinical safety and phase I studies of these agents by the industrial partners, one of the agents will be selected foray multicoated safety and tolerability phase II trial commencing at month 18.
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| PERSONS (20/20) |
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Werner POEWE (Contact / MEDIZINISCHE UNIVERSITAET INNSBRUCK (AT332 - Innsbruck) (Austria))
Johannes JAKOBSEN (Contact / AARHUS UNIVERSITETS HOSPITAL - AARHUS UNIVERSITY HOSPITAL (DK00D - Århus amt) (Denmark))
Alain HERIAUD (Contact / CENTRE HOSPITALIER ET UNIVERSITAIRE DE BORDEAUX (FR612 - Gironde) (France))
Jean-Pierre BASTARD (Contact / CENTRE HOSPITALIER UNIVERSITAIRE DE GRENOBLE (FR714 - Isère) (France))
William WAKEHAM (Contact / IMPERIAL COLLEGE LONDON (UK550 - Greater London) (Great Britain))
Mireille BLANC (Contact / INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR623 - Haute-Garonne) (France))
Jürgen WEBER (Contact / LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE212 - München, Kreisfreie Stadt) (Germany))
Sten WENNERSTROEM (Contact / LUNDS UNIVERSITET (SE043 - Malmoehus Laen) (Sweden))
Horst Franz KERN (Contact / PHILIPPS UNIVERSITAET MARBURG (DE724 - Marburg-Biedenkopf) (Germany))
Reinhard HOROSWSKI (Contact / SCHERING AG (DE300 - Berlin) (Germany))
Gabriel BARBASH (Contact / TEL AVIV SOURASKY MEDICAL CENTER (ME04 - Israel) (Israel))
Ruth LEVY (Contact / TEVA PHARMACEUTICAL INDUSTRIES LTD (ME04 - Israel) (Israel))
Jose Francisco DAVID FERREIRA (Contact / UNIVERSIDADE DE LISBOA (PT132 - Grande Lisboa) (Portugal))
Giampaolo CANTORE (Contact / UNIVERSITA DEGLI STUDI DI ROMA "LA SAPIENZA" (ITE43 - Roma) (Italy))
Hartmut WAGNER (Contact / UNIVERSITAET BONN (DEA22 - Bonn, Kreisfreie Stadt) (Germany))
Joaquim AZCON (Contact / UNIVERSITAT DE BARCELONA (ES511 - Barcelona) (Spain))
Robert WALKER (Contact / UNIVERSITY COLLEGE LONDON (UK550 - Greater London) (Great Britain))
Ignacio IRIBARREN (Contact / UNIVERSITY HOSPITAL "MARQUES DE VALDECILLA" (ES130 - Cantabria) (Spain))
Primoz RODE (Contact / UNIVERSITY MEDICAL CENTER LJUBLJANA (SI00E - Osrednjeslovenska) (Slovenia))
Mats Ola OTTOSSON (Contact / UPPSALA UNIVERSITET (SE021 - Uppsala län) (Sweden))
| RELATED NAVIGATION AREA(S) (2/2) |
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FP5 Life Quality
Neurosciences
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