13C-STARCH - Stable isotope applications to monitor starch digestion and fermentation for the development of functional foods. (LIFE QUALITY) (2002-01-01 - 2006-06-30) (»add to infobox)

Per Goeran NILSSON, Martine LAVILLE, Dominique POIROUX, Daniel RICHARD-MOLARD, Koenraad DEBACKERE, Elisabeth GRAY

LUNDS UNIVERSITET (SE043 - Malmoehus Laen) (Sweden), CENTRE DE RECHERCHE EN NUTRITION HUMAINE DE LYON (FR716 - Rhône) (France), GROUPE DANONE (FR101 - Paris) (France), HUMAN NUTRITION RESEARCH CENTRE OF NANTES (FR511 - Loire-Atlantique) (France), KATHOLIEKE UNIVERSITEIT LEUVEN (BE242 - Arr. Leuven) (Belgium), UNIVERSITY OF GLASGOW (UKA22 - Strathclyde) (Great Britain)

The aim of this project is to characterise the "metabolic quality" of carbohydrates, with the main focus on starch. With 13C-stable isotope techniques, 13C-glucose response to various 13C-starch sources will be studied, including functions that could modulate this response such as gastric emptying / intestinal transit time and digestion rates. These functions will be manipulated by addition of rat, protein, dietary fibre and enzyme inhibitors in order to optimise the glycemic response. Fermentation of 13C-starch in man will be characterised by measuring small intestinal bioavailability, 13C-short chain fatty acid production and bacterial flora. This project will lead to a rationale for the development of breakfast food / biscuits with the target groups healthy people, diabetic patients and people at risk to diabetes and obesity.

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