EUMORPHIA - Understanding human molecular physiology and pathology through integrated functional genomics in the mouse model (LIFE QUALITY) (2002-10-01 - 2006-03-31) (»add to infobox)

Nigel WATTS, Bruno ANDRAL, Josette ROGER, Mariano BARBACID, Mark LATHROP, Keith WILLIAMSON, David DAVISON, A MANDEL, Juergen KINDER, Alain STORK, Heather MARSHALL-HEYMAN, Rudi BALLING, Glauco TOCCHINI-VALENTINI, Anton BERNS, Domitien DEBOUZIE, Peter SUTER, Walter WAHLI, John ROGERS

MEDICAL RESEARCH COUNCIL (UK523 - Oxfordshire) (Great Britain), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR716 - Rhône) (France), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR246 - Loiret) (France), CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS (ES300 - Madrid) (Spain), CONSORTIUM NATIONAL DE RECHERCHE EN GENOMIQUE (FR104 - Essonne) (France), EUROPEAN MOLECULAR BIOLOGY LABORATORY (IT603 - Roma) (Italy), GENOME RESEARCH LTD (UK540 - Essex) (Great Britain), GROUPEMENT D'INTERET ECONOMIQUE - CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE (FR421 - Bas-Rhin) (France), GSF - FORSCHUNGSZENTRUM FUER UMWELT UND GESUNDHEIT GMBH (DE21H - München, Landkreis) (Germany), INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON (FR716 - Rhône) (France), KAROLINSKA INSTITUTET (SE010 - Stockholms län) (Sweden), NATIONAL CENTRE FOR BIOTECHNOLOGY (DE911 - Braunschweig, Kreisfreie Stadt) (Germany), NATIONAL RESEARCH COUNCIL OF ITALY (IT603 - Roma) (Italy), NETHERLANDS CANCER INSTITUTE/ANTONI VAN LEEUWENHOEK HOSPITAL (NL326 - Groot-Amsterdam) (Netherlands), UNIVERSITE CLAUDE BERNARD LYON 1 (FR716 - Rhône) (France), UNIVERSITY OF GENEVA (CH013 - Genève) (Switzerland), UNIVERSITY OF LAUSANNE (CH011 - Vaud) (Switzerland), UNIVERSITY OF MANCHESTER (UK820 - Greater Manchester) (Great Britain)

An integrated approach applying phenotyping, mutagenesis, informatics to development of mouse models/understanding of human physiology/disease, focusing on the development/standardisation of primary and secondary phenotyping protocols for all body systems in the mouse underpinned by substantial networking involving working groups from EU and abroad bringing expertise to bear in the development/validation of screens We will pilot novel approaches to gene-driven mutagenesis. The programme is supported by new informatics developments within research/networking focusing on provision of tools for dissemination, acquisition and querying of phenotype data. The training programme bolsters research bringing new skills from diverse areas e.g. veterinary and clinical medicine to mouse biology and the study of disease models, while also creating a new cadre of scientists trained in mouse genetics. EUMORPHIA prepares the EU community for future challenges re Genomes for Human Health.

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